Benzoyl chloride → HCID 836063、化合物
反応式
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][C:11]1[C:12]([Cl:17])=[N:13][CH:14]=[CH:15][CH:16]=1>N1C=CC=CC=1>[C:1]([NH:10][C:11]1[C:12]([Cl:17])=[N:13][CH:14]=[CH:15][CH:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
反応条件
- 温度
- -5 °C
実験手順
3.9 g (28 mmol) of benzoyl chloride are added to 30 ml of pyridine while the temperature is maintained at approximately -5° C. A solution containing 3 g (23.3 mmol) of 3-amino-2-chloropyridine in 20 ml of pyridine is added to this solution using a pressure equalizing funnel. The reaction medium is left stirring overnight and then poured into a water/ice mixture. The solid obtained is then filtered off, washed several times with water and thereafter recrystallized in absolute ethanol.
後処理
- additionis added to this solution
- waitThe reaction medium is left
- customThe solid obtained
- filtrationis then filtered off
- washwashed several times with water
- customrecrystallized in absolute ethanol
出典と根拠
- ORDレコード
- ord-edfbe51d03e64aa29e26919fd610f99c
- 出典データセット
- uspto-grants-1991_12
- 特許番号
- US05077408
反応ノート
読み込み中…