2H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo- → HCID 178442899、化合物

HRID 1462197ノート

反応式

HRID 1462197 の反応式
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[CH2:9]([NH2:27])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]/[CH:17]=[CH:18]\[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[CH2:9]([NH:27][C:5]1[CH2:6][O:1][NH:2][C:3](=[O:8])[N:4]=1)[CH2:10][CH2:11][CH:12]=[CH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

参加物

3

反応物 2

HCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-HCID 5356789Oleylamine

生成物 1

HCID 178442899HCID 178442899、化合物収率 16.4%

実験手順

To 0.66 g (0.005 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione dissolved in 10 ml of freshly distilled dry dioxane is added 1.33 g (0.0051 mole) of oleylamine. The reaction mixture is stirred for 17 hours at room temperature and the crystalline material filtered, washed with additional dry dioxane and chloroform, and dried to give 0.3 g (16 percent) of 5-(4-octadecenylamino)-6H-1,2,4-oxadiazin-3(2H)-one.

後処理

  1. distillationof freshly distilled dry dioxane
  2. filtrationthe crystalline material filtered
  3. washwashed with additional dry dioxane and chloroform
  4. customdried

出典と根拠

ORDレコード
ord-f780cc7bcec741a1980ac2d72229e5d4
出典データセット
uspto-grants-1984_07
特許番号
US04459403

反応ノート

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