HCID 20452406、化合物 → 2-Pyrrolidinone, 1-(3-hydroxy-4-methoxybenzoyl)-
反応式
C([O:8][C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:12]([N:14]1[CH2:18][CH2:17][CH2:16][C:15]1=[O:19])=[O:13])C1C=CC=CC=1>CO.[Pd]>[OH:8][C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:12]([N:14]1[CH2:18][CH2:17][CH2:16][C:15]1=[O:19])=[O:13]参加物
4
実験手順
2.0 g of 1-(3-benzyloxy-4-methoxybenzoyl)-2-pyrrolidinone are hydrogenated in 60 ml of absolute methanol with 0.5 g of 5% palladium/carbon under atmospheric pressure and at room temperature. The catalyst is filtered off and the filtrate is concentrated and stirred with diethyl ether. After filtration, there is obtained 1-(3-hydroxy-4-methoxybenzoyl)-2-pyrrolidinone of melting point 123°-125° C.
後処理
- filtrationThe catalyst is filtered off
- concentrationthe filtrate is concentrated
- filtrationAfter filtration
出典と根拠
- ORDレコード
- ord-d8bb651f64cb44d5a17224e3a0e8bb5d
- 出典データセット
- uspto-grants-1984_07
- 特許番号
- US04461906
反応ノート
読み込み中…