HCID 20452407、化合物 → 2-Pyrrolidinone, 1-(3-hydroxy-4-methoxybenzoyl)-

反応式

C([O:9][C:10]1[CH:11]=[C:12]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[C:13]([N:15]1[CH2:19][CH2:18][CH2:17][C:16]1=[O:20])=[O:14])(=O)C1C=CC=CC=1>C(OCC)(=O)C.[H][H].[Pd]>[OH:9][C:10]1[CH:11]=[C:12]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[C:13]([N:15]1[CH2:19][CH2:18][CH2:17][C:16]1=[O:20])=[O:14]

参加物

実験手順

150 mg of 1-(3-benzoyloxy-4-methoxybenzoyl)pyrrolin-2-one are dissolved in 100 ml of ethyl acetate and hydrogenated with hydrogen over 150 mg of 5% palladium/carbon at atmospheric pressure. The catalyst is filtered off and the filtrate is concentrated. The residue is stirred at room temperature in diethyl ether. After filtration, there is obtained 1-(3-hydroxy-4-methoxybenzoyl)-2-pyrrolidinone of melting point 122°-124° C.