HCID 3432930、化合物 → 2-(2-Chlorophenoxy)aniline

HRID 1464445ノート

反応式

HRID 1464445 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N+:15]([O-])=O.[H][H]>O1CCCC1.[Ni]>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH2:15]

参加物

5

反応物 2

HCID 3432930HCID 3432930、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 125690122-(2-Chlorophenoxy)aniline

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 2-chloro-(2-nitrophenoxy)benzene (5.00 g) in tetrahydrofuran (100 mL) was shaken in a Parr Hydrogenator over Raney nickel at 5 psi hydrogen at room temperature for 4 hours. The catalyst was filtered from the reaction, and the solution was evaporated under vacuum to a yellowish oil which crystallized on standing. The solid was crushed, suspended in hexane and filtered to yield the title compound as a light orange solid. Mp: 44°-45° C.

後処理

  1. filtrationThe catalyst was filtered from the reaction
  2. customthe solution was evaporated under vacuum to a yellowish oil which
  3. customcrystallized
  4. customThe solid was crushed
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-f4acf4c2855346cbaf1898ef75fb031c
出典データセット
uspto-grants-1994_04
特許番号
US05304644

反応ノート

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