2-(Benzyloxy)-6-butylpyridine → 6-Butylpyridin-2-ol

HRID 1471242

反応式

HRID 1471242 の反応式
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][CH2:16][CH2:17][CH3:18])[N:10]=1)C1C=CC=CC=1.[H][H]>[Pd].C(O)C>[CH2:15]([C:11]1[N:10]=[C:9]([OH:8])[CH:14]=[CH:13][CH:12]=1)[CH2:16][CH2:17][CH3:18]

参加物

5

反応物 2

HCID 666264812-(Benzyloxy)-6-butylpyridineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 233521006-Butylpyridin-2-ol

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a pressure reaction bottle were added 1.6 g 2-(benzyloxy)-6-butylpyridine, 0.2 g 5% palladium on carbon and 50 ml ethanol. The mixture was hydrogenated at 22 C and 40 psi hydrogen for 16 hours. Following filtration through celite and solvent removal, an oil was obtained that crystallized on standing to give 0.9 g.

後処理

  1. customTo a pressure reaction bottle
  2. filtrationfiltration through celite and
  3. customsolvent removal
  4. customan oil was obtained
  5. customthat crystallized
  6. customto give 0.9 g

出典と根拠

ORDレコード
ord-697c21211a3e4662a4f9c2bf6cbc246a
出典データセット
uspto-grants-2015_04
特許番号
US09011734B2

関連ノート

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