Sodium Carbonate → 1,4-Benzenedicarboxaldehyde, 2,5-dihydroxy-

HRID 1471325ノート

反応式

HRID 1471325 の反応式
C[O:2][C:3]1[CH:8]=[C:7]([CH:9]=[O:10])[C:6]([O:11]C)=[CH:5][C:4]=1[CH:13]=[O:14].B(Br)(Br)Br.C(=O)([O-])[O-].[Na+].[Na+]>ClC1C=CC=CC=1>[OH:2][C:3]1[CH:8]=[C:7]([CH:9]=[O:10])[C:6]([OH:11])=[CH:5][C:4]=1[CH:13]=[O:14]

参加物

5

反応物 3

HCID 10340Sodium CarbonateHCID 25134Boron tribromideHCID 6066482,5-Dimethoxyterephthalaldehyde

生成物 1

HCID 110842361,4-Benzenedicarboxaldehyde, 2,5-dihydroxy-

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

0.5 g of 2,5-dimethoxybenzene-1,4-dicarboaldehyde (AD) and 25 mL of boron tribromide were dissolved in 150 mL of chlorobenzene and stirred at room temperature for 12 hours. After complete reaction, the reacted mixture was neutralized with sodium carbonate, followed by extraction with water and dichloromethane and recrystallization within dichloromethane, thereby obtaining 2,5-dihydroxybenzene-1,4-dicarboaldehyde. The obtained product exhibited yield, property and NMR analysis result as follows.

後処理

  1. customAfter complete reaction
  2. extractionfollowed by extraction with water and dichloromethane and recrystallization within dichloromethane
  3. customThe obtained product exhibited yield
  4. customproperty and NMR analysis result

出典と根拠

ORDレコード
ord-a7cccfe99d784838bf2079719d6825a5
出典データセット
uspto-grants-2015_04
特許番号
US09012230B2

反応ノート

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