2-(Benzyloxy)-5-(methoxymethoxy)pyridine → HCID 178498305、化合物
反応式
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][O:17][CH3:18])=[CH:11][N:10]=1)C1C=CC=CC=1>CCO.[Pd]>[CH3:18][O:17][CH2:16][O:15][C:12]1[CH:13]=[CH:14][C:9]([OH:8])=[N:10][CH:11]=1参加物
4
実験手順
To 2-(benzyloxy)-5-(methoxymethoxy)pyridine (1.8 g, 8.71 mol) in EtOH was added Pd/C (1.0 g). The mixture was charged with H2 (15 psi), stirred at rt for 45 min, filtered, and concentrated to give 5-(methoxymethoxy)pyridin-2-ol (1.35 g, quantitative yield) as a pale yellow solid. LRMS (M+H+) m/z 156.1
後処理
- additionThe mixture was charged with H2 (15 psi)
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-cc7ab61bd8ca4d61808166c7062ba31d
- 出典データセット
- uspto-grants-2015_04
- 特許番号
- US09012450B2
反応ノート
読み込み中…