Sodium Iodide → 3-Iodopropyl-tris(trimethylsiloxy)silane

HRID 1478938ノート

反応式

HRID 1478938 の反応式
Cl[CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8].[I-:21].[Na+]>CC(C)=O>[I:21][CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8]

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 27578913-(3-Chloropropyl)-1,1,1,5,5,5-hexamethyl-3-((trimethylsilyl)oxy)trisiloxane

生成物 1

HCID 223256933-Iodopropyl-tris(trimethylsiloxy)silane収率 79.4%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

90 g of 3-chloropropyltris(trimethylsiloxy)silane (27) (Chem. Abstracts No. 18077-31-1) and 105.22 g of sodium iodide are added to 250 ml of acetone and stirred for 24 hours at reflux. The acetone is evaporated and the residue taken up in methylene chloride. The organic phase is washed with water, dried and evaporated. 89 g of the desired 3-iodopropyl-tris(trimethylsiloxy)silane (28) are obtained; 1H-NMR (ppm, CDCl3): 3.12 2H t, 1.75 2H txt, 0.43 2H t, 0 27H s.

後処理

  1. temperatureat reflux
  2. customThe acetone is evaporated
  3. washThe organic phase is washed with water
  4. customdried
  5. customevaporated

出典と根拠

ORDレコード
ord-991fa046e4424002a203c0a700519931
出典データセット
uspto-grants-2016_08
特許番号
US09403987B2

反応ノート

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