HCID 58455289、化合物 → 1,3-Dihydroxypropan-2-yl phenyl succinate

HRID 1479231ノート

反応式

HRID 1479231 の反応式
[C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:19])[CH2:2][CH2:3][C:4]([O:6][CH:7]1[CH2:12][O:11]C(C2C=CC=CC=2)[O:9][CH2:8]1)=[O:5]>C(O)C.[Pd]>[C:4]([O:6][CH:7]([CH2:12][OH:11])[CH2:8][OH:9])(=[O:5])[CH2:3][CH2:2][C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]

参加物

4

反応物 1

HCID 58455289HCID 58455289、化合物

生成物 1

HCID 584552561,3-Dihydroxypropan-2-yl phenyl succinate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Phenyl 2-phenyl-1,3-dioxan-5-yl succinate (0.11 g, 0.3 mmol) was dissolved in ethanol (20 ml) under argon and Pd/C (0.09 g, 0.1 mmol) was added. The flask was flushed with hydrogen and allowed to stir under 1 atm H2 at room temperature for 16 h. The crude reaction mixture was passed through a plug of celite and the solvent was removed under reduced pressure yielding (0.9 g, 0.26 mmol, 89%). The product was used without any further purification.

後処理

  1. customThe flask was flushed with hydrogen
  2. customThe crude reaction mixture
  3. customthe solvent was removed under reduced pressure
  4. customyielding (0.9 g, 0.26 mmol, 89%)
  5. customThe product was used without any further purification

出典と根拠

ORDレコード
ord-334dd724a2214bd7b923525dd7afdfd7
出典データセット
uspto-grants-2016_08
特許番号
US09408919B2

反応ノート

読み込み中…