Thionyl Chloride → HCID 178521139、化合物
反応式
[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][C:8]([OH:10])=O)[N:3]=[N:2]1.S(Cl)([Cl:13])=O>C(Cl)Cl>[NH:1]1[CH:5]=[C:4]([CH2:6][CH2:7][C:8]([Cl:13])=[O:10])[N:3]=[N:2]1参加物
4
実験手順
To a solution of 3-(1H-1,2,3-triazol-4-yl)propanoic acid (Example 19, step 2) (100 mg, 0.709 mmol) in DCM (5 mL) at RT under nitrogen was added thionyl chloride (0.621 mL, 8.50 mmol) and the reaction mixture stirred for 2 hours. The reaction mixture was concentrated under reduced pressure to afford the title product.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-a54b04e4bead41eea60d2d15797dc4fb
- 出典データセット
- uspto-grants-2016_08
- 特許番号
- US09409895B2
反応ノート
読み込み中…