ethyl (1R,2S)-2-phenylcyclopropane-1-carboxylate → (3-Phenylcyclopentyl)methanol

HRID 1485095

反応式

HRID 1485095 の反応式
C1([C@H]2C[C@H]2C(OCC)=O)C=CC=CC=1.C[O:16][C:17]([CH:19]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:20]1)=O>>[C:24]1([CH:21]2[CH2:22][CH2:23][CH:19]([CH2:17][OH:16])[CH2:20]2)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

参加物

3

反応物 2

HCID 816743ethyl (1R,2S)-2-phenylcyclopropane-1-carboxylateHCID 14093250Methyl 3-phenylcyclopentane-1-carboxylate

生成物 1

HCID 13354127(3-Phenylcyclopentyl)methanol収率 86.3%

実験手順

Instead of ethyl cis-2-phenylcyclopropanecarboxylate, 3-phenyl-cyclopentanecarboxylic acid methyl ester (1.76 g) was used and treated by the same technique as in Reference Example 23-1(2) to give (3-phenylcyclopentyl)methanol as a colorless oil (1.31 g).

後処理

  1. additiontreated by the same technique as in Reference Example 23-1(2)

出典と根拠

ORDレコード
ord-82d2a0acb592432c81810c3a9bb3555c
出典データセット
uspto-grants-2016_08
特許番号
US09422240B2

関連ノート

読み込み中…