4-Hydroxybenzaldehyde → HCID 178501257、化合物

反応式

OC1C=CC(C=O)=CC=1.C1(CCO)CC1.[C:16]1([OH:22])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.O[C@@H:24]1[CH2:29][CH2:28][C@H:27]([C:30]([O:32][CH3:33])=[O:31])[CH2:26][CH2:25]1>>[O:22]([C@H:24]1[CH2:29][CH2:28][C@H:27]([C:30]([O:32][CH3:33])=[O:31])[CH2:26][CH2:25]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

参加物

反応物 4

HCID 1264-Hydroxybenzaldehyde

HCID 996Phenol

HCID 1376422-Cyclopropylethan-1-ol

HCID 178501284HCID 178501284、化合物

生成物 1

HCID 178501257HCID 178501257、化合物収率 44.9%

実験手順

Instead of 4-hydroxybenzaldehyde and 2-cyclopropylethanol, phenol (1.43 g) and methyl cis-4-hydroxycyclohexanecarboxylate (2.00 g) were respectively used and treated by the same technique as in Reference Example 11-1 to give methyl trans-4-phenoxycyclohexanecarboxylate as a colorless oil (1.33 g).

後処理

additiontreated by the same technique as in Reference Example 11-1

出典と根拠

ORDレコード: ord-c23eedd4fc894509a899d44b497a8f48
出典データセット: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09422240B2

反応ノート

読み込み中…