Azetidine → 6-(Azetidin-1-yl)pyridine-3,4-diamine

反応式

[N:1]1([C:7]2[CH:12]=[C:11]([NH2:13])[C:10]([N+:14]([O-])=O)=[CH:9][N:8]=2)[CH2:6][CH2:5]OC[CH2:2]1.N1CCC1>>[N:1]1([C:7]2[N:8]=[CH:9][C:10]([NH2:14])=[C:11]([NH2:13])[CH:12]=2)[CH2:6][CH2:5][CH2:2]1

参加物

反応物 2

HCID 10422Azetidine

HCID 900216182-(Morpholin-4-yl)-5-nitropyridin-4-amine

生成物 1

HCID 900217496-(Azetidin-1-yl)pyridine-3,4-diamine

実験手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 151.1 and 151.2, except azetidine was used in place of morpholine.

出典と根拠

ORDレコード: ord-847fb57143484f2f97bab58b4da218d9
出典データセット: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09428502B2

反応ノート

読み込み中…