Hydrazine hydrate (1:1) → HCID 90029563、化合物

HRID 1488174ノート

反応式

HRID 1488174 の反応式
[CH3:1][CH:2]([C:5](=O)[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1)[CH:3]=O.O.[NH2:13][NH2:14]>C(O)C>[CH3:1][C:2]1[CH:3]=[N:13][NH:14][C:5]=1[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 90021327HCID 90021327、化合物2 回

生成物 1

HCID 90029563HCID 90029563、化合物収率 119.8%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
80 °C

実験手順

Into a 100-mL round-bottom flask, was placed a solution of 2-methyl-3-oxo-3-(tetrahydrofuran-3-yl)propanal (compound 263.3, 3.00 g, 19.2 mmol) in ethanol (25 mL). Hydrazine hydrate (1.16 mL, 24 mmol) was added and the resulting solution was stirred for 3 h at 80° C. The resulting mixture was concentrated under reduced pressure to obtain the title compound as a colorless oil (3.5 g, crude).

後処理

  1. customInto a 100-mL round-bottom flask, was placed
  2. concentrationThe resulting mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-550f9aca6b634bdca46f268ea30b6693
出典データセット
uspto-grants-2016_08
特許番号
US09428502B2

反応ノート

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