Propylamine → 2-(n-Decyl)imidazoline

HRID 1488794

反応式

HRID 1488794 の反応式
[C:1](#[N:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[Li].[CH2:14]([NH2:17])[CH2:15]C>C(N)CN>[CH2:2]([C:1]1[NH:12][CH2:15][CH2:14][N:17]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

参加物

5

反応物 3

HCID 7852Propylamine2 回HCID 16722Undecanenitrile2 回HCID 3028194Lithium

生成物 1

HCID 114994602-(n-Decyl)imidazoline収率 22%

試薬・触媒・溶媒 1

HCID 3301Ethylenediamine溶媒2 回

実験手順

Reduction of undecanenitrile in n-propylamine and ethylene-diamine. Lithium, (0.21 g, 30 mmol) in small pieces, was added to a stirred solution of undecanenitrile (0.84 g, 5 mmol) in n-propylamine and ethylenediamine (1.0 mL). The temperature began to rise after 20 min and reached 32° after 30 min and the reaction mixture turned blue. An aliquot of the reaction mixture showed no nitrile by glpc. The reaction mixture was poured over crushed ice and extracted with ethyl acetate (2×50 mL). After distillation of the ethyl acetate the residue deposited crystals. The crystals were collected and dried to give 2-(n-decyl)imidazoline (0.23 g, 22%)

後処理

  1. waitreached 32° after 30 min
  2. additionThe reaction mixture was poured
  3. customover crushed ice
  4. extractionextracted with ethyl acetate (2×50 mL)
  5. distillationAfter distillation of the ethyl acetate the residue
  6. customThe crystals were collected
  7. customdried

出典と根拠

ORDレコード
ord-e673198c27d0401f99ebe5ce08e77232
出典データセット
uspto-grants-1997_10
特許番号
US05675038

関連ノート

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