1-(Triisopropylsilyl)indole → HCID 11395451、化合物
反応式
CC(C)[Si](C(C)C)(C(C)C)n1ccc2ccccc21>B1Oc2ccccc2O1.CC(C)(O)C(C)(C)O.CCN(CC)CC.Cc1ccccc1.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F>CC(C)[Si](C(C)C)(C(C)C)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccccc21参加物
7
反応条件
- 温度
- 120 °C
実験手順
Prepared from N-(triisopropylsilyl)-1H-indole (4a, 54.7 mg, 0.200 mmol, 1.00 equiv) and catBH (96.0 mg, 0.800 mmol, 4.00 equiv) according to GP 2. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 6a (50.3 mg, 63%) as a slightly yellow oil.
出典と根拠
- ORDレコード
- ord-60618b7fc5b54d599ac4309f26d5cb76
- 出典データセット
- Borylation dataset from Roche
反応ノート
読み込み中…