2-Methyl-2,3-dihydro-1H-isoindol-1-one → 2-Methyl-6-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-2,3-dihydro-isoindol-1-one

HRID 1490848ノート

反応式

HRID 1490848 の反応式
CN1Cc2ccccc2C1=O>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.[Ir].[Ir]>CN1Cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1=O.CN1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1=O

参加物

7

反応物 1

HCID 2206572-Methyl-2,3-dihydro-1H-isoindol-1-one

生成物 2

HCID 468564162-Methyl-6-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-2,3-dihydro-isoindol-1-one収率 28%HCID 576912242-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one収率 26%

試薬・触媒・溶媒 4

HCID 2733548Bis(pinacolato)diborane試薬HCID 42491874,4'-Di-tert-butyl-2,2'-bipyridyl試薬HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium触媒HCID 7809P-Xylene溶媒

反応条件

温度
35 °C

出典と根拠

ORDレコード
ord-4d9439b94bfa4113b4442f24c09c900d
出典データセット
Borylation dataset from Roche

反応ノート

読み込み中…