3-Ethyl-(1-thiaethyl)-benzene → HCID 177499506、化合物

HRID 1491148ノート

反応式

HRID 1491148 の反応式
CCc1cccc(SC)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.FC(F)(F)C1COB(c2ccccc2-c2ccc(-c3ccccn3)nc2)O1.[Ir].[Ir]>CCc1ccc(B2OC(C)(C)C(C)(C)O2)c(SC)c1

参加物

6

反応物 1

HCID 149441333-Ethyl-(1-thiaethyl)-benzene

生成物 1

HCID 177499506HCID 177499506、化合物収率 88%

試薬・触媒・溶媒 4

HCID 2733548Bis(pinacolato)diborane試薬HCID 1349566232-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine試薬HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium触媒HCID 7809P-Xylene溶媒

反応条件

温度
55 °C

実験手順

Ligand 3f: A mixture of ortho- and meta-borylated products (122 mg, 88% yield, ortho/meta + para = >30); ortho-borylated product 4k was obtained by further purification by GPC (111 mg, 80% yield), colorless oil;

出典と根拠

ORDレコード
ord-62cafbeae78042f3a2ec3f143cfb6c2c
出典データセット
Borylation dataset from Roche

反応ノート

読み込み中…