Benzonitrile, 4-(trifluoromethyl)- → 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzonitrile

HRID 1491461ノート

反応式

HRID 1491461 の反応式
N#Cc1ccc(C(F)(F)F)cc1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OBOC1(C)C.CCCCCC.C[OH2+].C[OH2+].[Ir].[Ir]>CC1(C)OB(c2cc(C(F)(F)F)ccc2C#N)OC1(C)C

参加物

6

反応物 1

HCID 67995Benzonitrile, 4-(trifluoromethyl)-

生成物 1

HCID 569731072-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzonitrile収率 68%

試薬・触媒・溶媒 4

HCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane試薬HCID 42491874,4'-Di-tert-butyl-2,2'-bipyridyl試薬HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium触媒HCID 8058Hexane溶媒

反応条件

温度
25 °C

出典と根拠

ORDレコード
ord-6a067bf346cd4496a97749228fc9bcee
出典データセット
Borylation dataset from Roche

反応ノート

読み込み中…