Hydrogen Peroxide → HCID 11819636、化合物
反応式
OO.[C:3]([NH:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)(=[O:5])[CH3:4].S([O-])([O-])=[O:16].[Na+].[Na+]>C(O)(=O)C>[C:3]([NH:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N+:10]=1[O-:16])(=[O:5])[CH3:4]参加物
5
実験手順
30 wt % Hydrogen peroxide (80.3 ml) was added dropwise to a solution of 2-(2-acetylaminoethyl)pyridine (64.5 g) in acetic acid (65 ml) at 70°-75° C. and the mixture was stirred at the same temperature for 8 hours. After the mixture was ice-cooled and the mixture was added to a mixture of sodium sulfite (56.9 g) in ice water (200 ml). The solvent was removed by concentration in vacuo and the residue was extracted with a tetrahydrofuran. The extract solution was dried over magnesium sulfate and evaporated to give 2-(2-acetylaminoethyl)pyridine N-oxide (70.82 g).
後処理
- temperaturecooled
- customThe solvent was removed by concentration in vacuo
- extractionthe residue was extracted with a tetrahydrofuran
- dry with materialThe extract solution was dried over magnesium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-691489eef06f4391a092e1a41c2e48a9
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05371097
反応ノート
読み込み中…