2-(3-Benzyloxypropyl)-3-hydroxy-gamma-butyrolactone → 2-(3-Hydroxypropyl)-3-hydroxy-gamma-butyrolactone
反応式
C([O:8][CH2:9][CH2:10][CH2:11][CH:12]1[CH:17]([OH:18])[CH2:16][O:15][C:13]1=[O:14])C1C=CC=CC=1>C(O)C.C(O)(=O)C.[Pd]>[OH:8][CH2:9][CH2:10][CH2:11][CH:12]1[CH:17]([OH:18])[CH2:16][O:15][C:13]1=[O:14]参加物
4
実験手順
A solution of 18.7 g of 2-(3-benzyloxypropyl)-3-hydroxy-γ-butyrolactone in 90 ml of ethanol-acetic acid (2:1) is hydrogenated over 640 mg of 10% palladium on carbon at 45 psi for 20 h. The catalyst is filtered and the filtrates are evaporated to give 2-(3-hydroxypropyl)-3-hydroxy-γ-butyrolactone as an oil.
後処理
- filtrationThe catalyst is filtered
- customthe filtrates are evaporated
出典と根拠
- ORDレコード
- ord-010b69b71e544316854b40939d0eaf01
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05371096
反応ノート
読み込み中…