反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1.[C:14](#[N:18])[CH:15]([CH3:17])[CH3:16].[Cl-].[Al+3].[Cl-].[Cl-]>>[O:11]1[CH2:12][CH2:13][N:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH:1][C:14](=[NH:18])[CH:15]([CH3:17])[CH3:16])[CH2:9][CH2:10]1参加物
4
実験手順
A mixture of 4-(2-aminophenyl)morpholine (5.34 g), isobutyronitrile (6 g) and anhydrous aluminium chloride (12 g) was heated at 160°-170° C. for 6 hours to give N-(2-morpholinophenyl)isobutyramidine (m.p. 138° C.) which was recrystallised from a 1:1 mixture of ethylacetate and hexane.
後処理
- temperaturewas heated at 160°-170° C. for 6 hours
出典と根拠
- ORDレコード
- ord-dc2260a1437242ecacff361fbb87fda7
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05373008
関連ノート
読み込み中…