Benzylamine → Pentan-2-YL 4-hydroxybenzoate
反応式
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH:14]([CH3:18])[CH2:15][CH2:16][CH3:17])=[O:12])=[CH:7][CH:6]=1)(=O)C.C(N)C1C=CC=CC=1>C(O)C.C(Cl)(Cl)Cl>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]([O:13][CH:14]([CH3:18])[CH2:15][CH2:16][CH3:17])=[O:12])=[CH:9][CH:10]=1参加物
5
実験手順
Two grams of the crude compound (2) was dissolved in 50 ml of ethanol and 4 g of benzylamine was added dropwise. The mixture was stirred at room temperature for 4 hours, then diluted with 500 ml of chloroform, washed with dilute hydrochloric acid and water in this order, and dried with magnesium sulfate. After the solvent was evaporated, the residue was subjected to isolation and purification by silica gel column chromatography to obtain 1.6 g of a final compound.
後処理
- washwashed with dilute hydrochloric acid and water in this order
- dry with materialdried with magnesium sulfate
- customAfter the solvent was evaporated
- customthe residue was subjected to isolation and purification by silica gel column chromatography
出典と根拠
- ORDレコード
- ord-1d632962eec24eb9be4f8d0db8c50c8f
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05374375
反応ノート
読み込み中…