反応式
[C@@H]1([N:9]2[CH:17]=[C:15]([CH3:16])[C:13](=[O:14])NC2=O)O[C@H](CO)[C@@H](O)C1.C1N(CCO)CCN(CCS(O)(=O)=O)C1.C1N=C(N)C2N=CN([C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H](N5C=C(C(N)=O)CC=C5)[C@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)C=2N=1.C1C=[N+]([C@@H]2O[C@H](COP(OP(OC[C@H]3O[C@@H](N4C5N=CN=C(N)C=5N=C4)[C@H](OP(O)(O)=O)[C@@H]3O)(O)=O)(O)=O)[C@@H](O)[C@H]2O)C=C(C(N)=O)C=1.C(C=C)=O.CCN(C(SSC(N(CC)CC)=S)=S)CC.C(=O)CC.[CH:149](=O)[C:150]1[CH:155]=[CH:154][CH:153]=[CH:152][CH:151]=1>>[CH2:155]([C:150]1[CH:149]=[CH:16][C:15]([CH:13]=[O:14])=[C:17]([NH2:9])[C:151]=1[CH2:152][CH3:153])[CH3:154]参加物
9
実験手順
Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal supplied by the Department of Pharmaceutical Development at our Institute. [3H]-Thymidine was purchased from New England Nuclear, Boston, Mass. Concanavalin A, horse serum, RPMI-1640 and HEPES were from Gibco, Grand Island, N.Y. NAD and NADP were purchased from Boehringer, Mannheim. Acrolein and disulfiram were obtained from Aldrich Chemical Co., Milwaukee, Wis. Propionaldehyde and benzaldehyde were from Eastman Kodak Chemical Co., Rochester, N.Y. Diethyl aminobenzaldehyde (DEAB) was kindly provided by Dr. John Hilton, Johns Hopkins School of Medicine, Baltimore, Md.
後処理
- customMaterials: SDA was prepared by acid hydrolysis of the corresponding bioacetal
出典と根拠
- ORDレコード
- ord-5424f1799aac4456a064308777a3601d
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05374658
関連ノート
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