Epinephrine → Dopamine

HRID 1492750

反応式

HRID 1492750 の反応式
C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[CH:14]1[C:19]([C@@H:20](O)[CH2:21][NH2:22])=[CH:18][C:17]([OH:24])=[C:16]([OH:25])[CH:15]=1.CNC[C@H](O)C1C=CC(O)=C(O)C=1>C(#N)C>[NH2:22][CH2:21][CH2:20][C:19]1[CH:14]=[CH:15][C:16]([OH:25])=[C:17]([OH:24])[CH:18]=1

参加物

5

反応物 3

HCID 5816EpinephrineHCID 31348CitrateHCID 439260Norepinephrine

生成物 1

HCID 681Dopamine収率 96.9%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

The results shown in FIGS. 6 and 7 were obtained using a solvent of 95% 0.05 m citrate buffer with a pH of 5.2 and 5% acetonitrile with a flow rate of 0.8 ml/min. In FIGS. 6 and 7, peak 1 represents the solvent front, peak 2 represents 4.9 ng norepinephrine and peak 3 represents 4.88 ng epinephrine. Peak 4 was produced by dopamine (4.30 ng).

後処理

  1. custom6 and 7 were obtained

出典と根拠

ORDレコード
ord-a4d2c75e019745efb68ff20089f38f71
出典データセット
uspto-grants-1994_12
特許番号
US05374892

関連ノート

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