Hydrochloric Acid → HCID 54206520、化合物

HRID 1494296ノート

反応式

HRID 1494296 の反応式
[NH2:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][CH2:7][C:8]2[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:9]=2[OH:10])=[CH:4][CH:3]=1.CC(N(C)C)=O.[CH2:24]([S:32](Cl)(=[O:34])=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].Cl>N1C=CC=CC=1>[CH2:24]([S:32]([NH:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][CH2:7][C:8]2[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:9]=2[OH:10])=[CH:4][CH:3]=1)(=[O:34])=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 31374DimethylacetamideHCID 822611-Octanesulfonyl chlorideHCID 125250502-[2-(4-Aminophenyl)ethyl]-1,4-benzenediol

生成物 1

HCID 54206520HCID 54206520、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

In 1 l-volume three-necked flask were charged 100 g of (4-aminophenethyl)hydroquinone, 500 ml of dimethylacetamide, and 36 ml of pyridine, and 85 ml of octanesulfonyl chloride were slowly added dropwise thereto at room temperature while stirring. After the dropwise addition, the stirring was continued for 4 hours. The reaction mixture was poured into a hydrochloric acid aqueous solution and extracted with ethyl acetate. The extract was washed with water, dried over magnesium sulfate, and concentrated to obtain 129 g of the entitled compound as an oily substance.

後処理

  1. additionwere slowly added dropwise
  2. additionAfter the dropwise addition
  3. extractionextracted with ethyl acetate
  4. washThe extract was washed with water
  5. dry with materialdried over magnesium sulfate
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-2558cc6cc1274ea9bd819c6873c27e45
出典データセット
uspto-grants-1991_06
特許番号
US05026634

反応ノート

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