Ethyl benzoylacetate → HCID 178519489、化合物

HRID 1494319ノート

反応式

HRID 1494319 の反応式
NC1C=[N+]([O-])C=CC=1.C(CC(OCC)=O)(=O)C1C=CC=CC=1.C([O-])([O-])OCC.[C:29]([C:37]1[CH:38]=[N:39][C:40]2[C:45]([C:46]=1[OH:47])=[N:44][CH:43]=[CH:42][CH:41]=2)(=[O:36])[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[C:29]([C:37]1[CH:38]=[N:39][C:40]2[C:41]([C:46]=1[OH:47])=[CH:42][CH:43]=[N:44][CH:45]=2)(=[O:36])[C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1

参加物

5

反応物 4

HCID 7170Ethyl benzoylacetateHCID 1231253-Pyridinamine, 1-oxideHCID 53630039EthylorthoformateHCID 178519484HCID 178519484、化合物

生成物 1

HCID 178519489HCID 178519489、化合物収率 70%

実験手順

The 7-oxide of 3-benzoyl 4-hydroxy 1,7-naphthyridine is prepared from 3-aminopyridine 1-oxide described by J. C. Murray and C. R. Hauser in J. Org. Chem. p. 2008-14 (1954), ethyl benzoylacetate and ethyl orthoformate according to the process described for 3-benzoyl 4-hydroxy 1,5-naphthyridine; this product is obtained in 70% yield, m.p. >260° C.

後処理

  1. customthis product is obtained in 70% yield, m.p. >260° C.

出典と根拠

ORDレコード
ord-dc0e93acb0114f1b985cd4acaa63c5df
出典データセット
uspto-grants-1991_06
特許番号
US05026711

反応ノート

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