1-(4-(3-Ethoxy-4-nitrophenyl)piperazin-1-yl)ethanone → 1-(4-(4-Amino-3-ethoxyphenyl)piperazin-1-yl)ethanone
反応式
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([N:13]2[CH2:18][CH2:17][N:16]([C:19](=[O:21])[CH3:20])[CH2:15][CH2:14]2)[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)[CH3:2]>C(O)C.[Pd]>[NH2:10][C:9]1[CH:8]=[CH:7][C:6]([N:13]2[CH2:18][CH2:17][N:16]([C:19](=[O:21])[CH3:20])[CH2:15][CH2:14]2)=[CH:5][C:4]=1[O:3][CH2:1][CH3:2]参加物
4
実験手順
The compound prepared in Step 2 was dissolved in ethanol, added with 10% Pd/C and stirred under hydrogen atmosphere for 2 hours. Upon completion of the reaction, the Pd/C in the reaction mixture was removed using celite and the solvent was removed under reduced pressure. The thus obtained compound was used in the subsequent reaction without further purification.