Sodium Hydroxide → 6-Chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acid
反応式
C([O:3][C:4]([C:6]1[C:7]([O:23][CH:24]2[CH2:28][CH2:27][CH2:26][CH2:25]2)=[N:8][C:9]2[C:14]([C:15]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[CH:13][C:12]([Cl:22])=[CH:11][CH:10]=2)=[O:5])C.[OH-].[Na+]>C(O)C>[Cl:22][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([O:23][CH:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1)[C:6]([C:4]([OH:5])=[O:3])=[C:15]2[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1参加物
4
実験手順
The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. Off white solid (28.5 mg, 77%). LC-MS: 368 (M+H)+.