Sodium Hydroxide → HCID 71556882、化合物
反応式
C([O:3][C:4]([C:6]1[C:7]([CH:26]([CH3:28])[CH3:27])=[N:8][C:9]2[C:14]([C:15]=1[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23])=[CH:13][C:12]([Cl:24])=[CH:11][C:10]=2[CH3:25])=[O:5])C.[OH-].[Na+]>C(O)C>[Cl:24][C:12]1[CH:13]=[C:14]2[C:9](=[C:10]([CH3:25])[CH:11]=1)[N:8]=[C:7]([CH:26]([CH3:28])[CH3:27])[C:6]([C:4]([OH:5])=[O:3])=[C:15]2[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23]参加物
4
実験手順
The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-4-(2-chloro-benzyl)-2-isopropyl-8-methyl-quinoline-3-carboxylic acid ethyl ester (50 mg, 0.12 mmol) and 1N NaOH in ethanol. Off white solid (18 mg, 39%). LC-MS (ESI): 388 (M+H)+.
出典と根拠
- ORDレコード
- ord-ea26e2e6f89945a4bec112f638cdcc03
- 出典データセット
- uspto-grants-2015_12