N-Iodosuccinimide → HCID 117600656、化合物
反応式
[CH3:1][O:2][C:3]1[CH:7]=[C:6]([CH3:8])[O:5][N:4]=1.[I:9]N1C(=O)CCC1=O>CC(O)=O>[I:9][C:7]1[C:3]([O:2][CH3:1])=[N:4][O:5][C:6]=1[CH3:8]参加物
4
反応条件
- 温度
- 60 °C
実験手順
To a solution of 3-Methoxy-5-methyl-isoxazole (0.60 g, 5.0 mmol) in AcOH (15 mL) is added N-iodosuccinimide (1.10 g, 5.00 mmol) at 60° C. under nitrogen. Then the reaction mixture is stirred at 60° C. for 2 h. The mixture is concentrated in vacuo to give an oil. This oil is purified by column chromatography on silica gel to give the desired compound.
後処理
- concentrationThe mixture is concentrated in vacuo
- customto give an oil
- customThis oil is purified by column chromatography on silica gel
出典と根拠
- ORDレコード
- ord-5096fc4612af49eba601f5debdcd0d7f
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09199988B2
反応ノート
読み込み中…