Hydrochloric Acid → HCID 15116074、化合物
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:10]=[C:11]([C:15]([O:17]CC)=[O:16])[N:12]([CH3:14])[N:13]=1.[OH-].[Na+].Cl>C(O)C>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:10]=[C:11]([C:15]([OH:17])=[O:16])[N:12]([CH3:14])[N:13]=1参加物
5
実験手順
Ethyl 5-(2,4-dichlorophenyl)-2-methyl-2H-pyrazole-3-carboxylate (2.98 g) was added to ethanol (50 ml), and sodium hydroxide (5.0 g) was added thereto at a room temperature under stirring, and subsequently the mixture was heated and stirred for 60 minutes. The mixture was adjusted to pH 5 by addition of 2-N hydrochloric acid, and the precipitated crystal was separated by filtration and subjected to through circulation drying to give the title compound (1.90 g, 70%) as a white powder.
後処理
- additionwas added
- temperaturesubsequently the mixture was heated
- stirringstirred for 60 minutes
- customthe precipitated crystal was separated by filtration
- customdrying
出典と根拠
- ORDレコード
- ord-dc3d2d80647d4b718084c8af9b1a2455
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09200008B2
反応ノート
読み込み中…