Water → 4-Benzenesulfinyl-benzoic acid

HRID 1501010ノート

反応式

HRID 1501010 の反応式
[C:1]1([S:7][C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br-].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.[OH2:50]>N1C=CC=CC=1>[C:1]1([S:7]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)=[O:50])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 962WaterHCID 2385984-(Phenylthio)benzoic acidHCID 17977687Phenyltrimethylammonium bromide dibromide

生成物 1

HCID 3438114-Benzenesulfinyl-benzoic acid

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
20 °C

実験手順

To a suspension of 4-(phenylthio)benzoic acid (800 mg, 3.5 mmol) in pyridine (5 mL) and water (5 mL) was added N-phenyl-N,N,N-trimethylammonium tribromide (1.4 g, 3.7 mmol). The mixture was stirred at 20° C. for 12 hours. Then the solvent was evaporated in vacuo to give 4-(phenylsulfinyl)benzoic acid which was used directly without further purification. LRMS (M+H)− m/z: calcd 246.04. found 246.

後処理

  1. customThen the solvent was evaporated in vacuo

出典と根拠

ORDレコード
ord-f5d9c31ce0144005bfdc5ef58b15cb6b
出典データセット
uspto-grants-2015_12
特許番号
US09206128B2

反応ノート

読み込み中…