Sodium Hydroxide → 2,4-Thiazolidinedicarboxylic acid, 3-acetyl-2-methyl-
反応式
CC[O:3][C:4]([C:6]1([CH3:17])[N:10]([C:11](=[O:13])[CH3:12])[CH:9]([C:14]([OH:16])=[O:15])[CH2:8][S:7]1)=[O:5].[OH-].[Na+]>C(O)C>[C:11]([N:10]1[CH:9]([C:14]([OH:16])=[O:15])[CH2:8][S:7][C:6]1([CH3:17])[C:4]([OH:5])=[O:3])(=[O:13])[CH3:12]参加物
4
実験手順
The crude product (10.19 g) of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester, which was obtained by a method similar to that in Synthetic Example 13, was dissolved in ethanol (20 ml), and 4N NaOH was added thereto. The mixture was stirred under an argon atmosphere, and ethanol was added thereto to give a pale-yellow solid. The obtained solid was collected by filtration to give N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2Na salt (trans form) as crystals (9.09 g, about 72%).
後処理
- customto give a pale-yellow solid
- filtrationThe obtained solid was collected by filtration
出典と根拠
- ORDレコード
- ord-c1d38f46b4394190babe09992a69420b
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09212154B2
反応ノート
読み込み中…