m-Chloroperbenzoic acid → HCID 178526232、化合物
反応式
ClC1C=CC=C(C(OO)=[O:9])C=1.[Br:12][C:13]1[CH:14]=[C:15]2[N:21]=[CH:20][NH:19][C:16]2=[N:17][CH:18]=1>C(OCC)(=O)C>[Br:12][C:13]1[CH:14]=[C:15]2[N:21]=[CH:20][NH:19][C:16]2=[N+:17]([O-:9])[CH:18]=1参加物
4
実験手順
m-Chloroperbenzoic acid (25 wt % water content, 2.77 g, 12.0 mmol) was gradually added dropwise to 6-bromo-3H-imidazo[4,5-b]pyridine (1.58 mg, 7.98 mmol) in ethyl acetate (15 mL), and the reaction mixture was stirred at room temperature for one day. The precipitated solid was collected by filtration and washed with ethyl acetate and diethyl ether and dried under reduced pressure to give the title compound as a pale yellow solid (1.67 g, yield 98%).
後処理
- filtrationThe precipitated solid was collected by filtration
- washwashed with ethyl acetate and diethyl ether
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-86d93005289b43f39430e39ef5af3d7b
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09216999B2
反応ノート
読み込み中…