Sodium Hydroxide → HCID 61834499、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([NH:16]C(=O)C)[CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9].[OH-].[Na+]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9])[NH2:16]参加物
3
反応条件
- 温度
- 65 °C
実験手順
700.0 mg (2.67 mmol) N-[3-methyl-4-(morpholin-4-yl-carbonyl)-phenyl]-acetamide are combined with 7 ml 4-molar sodium hydroxide solution and stirred overnight at 65° C. The reaction mixture is poured onto ice water and extracted with ethyl acetate. The organic phase is dried over magnesium sulphate and evaporated down i. vac.
後処理
- additionThe reaction mixture is poured onto ice water
- extractionextracted with ethyl acetate
- dry with materialThe organic phase is dried over magnesium sulphate
- customevaporated down i
出典と根拠
- ORDレコード
- ord-0aa6374f81f648318495f33d600113bb
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07732466B2
反応ノート
読み込み中…