4-amino-N-(3,4-dimethylphenyl)-3-nitrobenzamide → HCID 66965643、化合物
反応式
[NH2:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[C:11]([CH3:16])[CH:10]=2)=[O:7])=[CH:4][C:3]=1[N+:19]([O-])=O>CCO.O=[Pt]=O>[NH2:19][C:3]1[CH:4]=[C:5]([CH:17]=[CH:18][C:2]=1[NH2:1])[C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[C:11]([CH3:16])[CH:10]=1)=[O:7]参加物
4
実験手順
A solution of 4-amino-N-(3,4-dimethylphenyl)-3-nitro-benzamide (2.0 g) in EtOH (40 mL) was hydrogenated at 1 atm over PtO2 (200 mg, 10% w) for 18 hrs. The catalyst was filtered through Celite and the solvent was removed under reduced pressure to afford 3,4-diamino-N-(3,4-dimethylphenyl)-benzamide as a yellow solid. MS (ESI)m/z 256 (M+H).
後処理
- filtrationThe catalyst was filtered through Celite
- customthe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-cc3c84a6526849fe929ea89825ac959b
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08222248B2
反応ノート
読み込み中…