Ethanol → HCID 21224573、化合物

HRID 1517130ノート

反応式

HRID 1517130 の反応式
[OH:1][CH2:2][C:3]1[O:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=1.[H][H].O[CH2:13][C:14]1OC(CO)=CC=1.[CH2:21](O)[CH3:22]>[Pt]>[CH2:13]([O:8][CH2:7][C:6]1[O:9][C:3]([CH2:2][O:1][CH2:21][CH3:22])=[CH:4][CH:5]=1)[CH3:14]

参加物

6

反応物 4

HCID 702EthanolHCID 746632,5-Furandimethanol2 回HCID 2373325-(Hydroxymethyl)furfuralHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 21224573HCID 21224573、化合物収率 75%

試薬・触媒・溶媒 1

HCID 23939Platinum触媒

実験手順

In a 7.5 ml batch reactor, 0.06 mmol 5-(hydroxymethyl)furfural (HMF) in 1 mL ethanol and 5 bars of hydrogen was reacted with 3 mol % of a Pt/C catalyst for 2 days at room temperature. The starting material was completely converted in 100% selectivity to 2,5-di(hydroxymethyl)furan. Subsequently, the mixture was heated to 75° C. for 1 day without hydrogen. The 2,5-di(hydroxymethyl)furan was fully converted and 2,5-bis(ethoxymethyl)furan was obtained in 75% yield. 25% Side products are ring opened levulinate derivatives. The experiment was successfully repeated on a 20 gram scale.

出典と根拠

ORDレコード
ord-127917b3d2a543319fb9bf5f31875246
出典データセット
uspto-grants-2012_07
特許番号
US08231693B2

反応ノート

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