Nitric Acid → N-(2-nitro-4-propanoylphenyl)acetamide
反応式
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12](=[O:14])[CH3:13])=[CH:7][CH:6]=1)(=[O:4])[CH2:2][CH3:3].[N+:15]([O-])([OH:17])=[O:16]>>[N+:15]([C:7]1[CH:6]=[C:5]([C:1](=[O:4])[CH2:2][CH3:3])[CH:10]=[CH:9][C:8]=1[NH:11][C:12](=[O:14])[CH3:13])([O-:17])=[O:16]参加物
3
反応条件
- 温度
- -20 °C
実験手順
To 140 ml of nitric acid are added portionwise, while maintaining the temperature at −20° C., 37.8 g (198 mM) of N-(4-propanoylphenyl)acetamide. The reaction medium is then poured into a water/ice mixture. The solid that precipitates out is filtered off and washed with water to give, after drying, 37.6 g of N-(2-nitro-4-propanoylphenyl)acetamide in the form of a pale yellow solid.
後処理
- customThe solid that precipitates out
- filtrationis filtered off
- washwashed with water
- customto give
- customafter drying
出典と根拠
- ORDレコード
- ord-41d0d4c94496460aa197a33c470bec73
- 出典データセット
- uspto-grants-2012_07
- 特許番号
- US08232272B2
反応ノート
読み込み中…