Phthalimide → 2-[[2-[4-[(2-chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]-3-pyridyl]methyl]isoindoline-1,3-dione

反応式

N(C(OC(C)C)=O)=NC(OC(C)C)=O.[Cl:15][C:16]1[S:20][C:19]2[C:21]3([O:42][CH2:43][C:44]([F:46])([F:45])[C:18]=2[CH:17]=1)[CH2:26][CH2:25][N:24]([CH2:27][C:28]1[C:29]([CH3:41])=[N:30][N:31]([C:33]2[C:38]([CH2:39]O)=[CH:37][CH:36]=[CH:35][N:34]=2)[CH:32]=1)[CH2:23][CH2:22]3.[C:47]1(=[O:57])[NH:51][C:50](=[O:52])[C:49]2=[CH:53][CH:54]=[CH:55][CH:56]=[C:48]12.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C1(C)C=CC=CC=1>[Cl:15][C:16]1[S:20][C:19]2[C:21]3([O:42][CH2:43][C:44]([F:45])([F:46])[C:18]=2[CH:17]=1)[CH2:22][CH2:23][N:24]([CH2:27][C:28]1[C:29]([CH3:41])=[N:30][N:31]([C:33]2[C:38]([CH2:39][N:51]4[C:47](=[O:57])[C:48]5[C:49](=[CH:53][CH:54]=[CH:55][CH:56]=5)[C:50]4=[O:52])=[CH:37][CH:36]=[CH:35][N:34]=2)[CH:32]=1)[CH2:25][CH2:26]3