Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester → Hydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

HRID 1518174

反応式

HRID 1518174 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:21]2[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][C:22]=2[Cl:28])=[C:6]([O:8][C:9](=[O:19])[CH2:10][O:11]CC2C=CC=CC=2)[CH:7]=1>CO.[Pd]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:21]2[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][C:22]=2[Cl:28])=[C:6]([O:8][C:9](=[O:19])[CH2:10][OH:11])[CH:7]=1

参加物

4

反応物 1

HCID 57667396Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

生成物 1

HCID 57667367Hydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester 4 (5 grams) was dissolved in methanol (50 mL) in a pressure vessel, palladium on carbon (5%, 5 grams) was added and the mixture was stirred under an atmosphere of hydrogen (4 Kg) for 4 hours. The catalyst was removed by filtration and the methanol was distilled off to yield crude 5.

後処理

  1. customThe catalyst was removed by filtration
  2. distillationthe methanol was distilled off
  3. customto yield crude 5

出典と根拠

ORDレコード
ord-3a5c37b98057400886749780a484c000
出典データセット
uspto-grants-2012_07
特許番号
US08232422B2

関連ノート

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