Pyridine → HCID 118202506、化合物
反応式
N[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].[C:11]([O:17][C:18]1[CH:23]=[CH:22][C:21]([S:24](Cl)(=[O:26])=[O:25])=[CH:20][CH:19]=1)(=[O:16])[C:12]([CH3:15])([CH3:14])[CH3:13].[N:28]1C=CC=CC=1>>[C:11]([O:17][C:18]1[CH:23]=[CH:22][C:21]([S:24](=[O:26])(=[O:25])[NH:28][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:3](=[O:4])[CH3:2])=[CH:20][CH:19]=1)(=[O:16])[C:12]([CH3:15])([CH3:14])[CH3:13]参加物
4
実験手順
2-Aminoacetophenone (1 mmol) and p-pivaloyloxybenzenesulfonyl chloride (1.5 equivalent weights) were added into pyridine (5 mL) to obtain a mixture, followed by subjecting to reaction at room temperature for 4 hours and then removing pyridine under vacuum to obtain a reaction product. The reaction product was purified using a silica gel column (n-hexane/acetone=4:1), thereby obtaining 4-(N-(2-acetylphenyl)sulfamoyl)phenyl pivalate (331 mg, yield 89%).