Dichloromethane → (2S,4S)-2-(3-Chloro-2-fluoro-benzylcarbamoyl)-4-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
反応式
C[O:2][C:3]([C@H:5]1[CH2:9][C@@H:8]([C:10](=[O:21])[NH:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:14]=2[F:20])[N:7]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:6]1)=O.[BH4-].[Li+].C(Cl)Cl>C1COCC1.[Cl-].[Na+].O>[C:25]([O:24][C:22]([N:7]1[CH2:6][C@@H:5]([CH2:3][OH:2])[CH2:9][C@H:8]1[C:10](=[O:21])[NH:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[C:14]=1[F:20])=[O:23])([CH3:28])([CH3:26])[CH3:27]参加物
6
