Tetrahydrofuran → (2S,4R)-1-(1-carbamoyl-1H-indol-3-ylcarbamoyl)-4-fluoro-pyrrolidine-2-carboxylic acid benzyl ester

反応式

OC(C(F)(F)F)=O.[CH2:8]([O:15][C:16]([C@@H:18]1[CH2:22][C@@H:21]([F:23])[CH2:20][NH:19]1)=[O:17])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[N:24]([C:27]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[N:29]([C:36]([NH2:38])=[O:37])[CH:28]=1)=[C:25]=[O:26].C1COCC1.C(N(CC)CC)C>O>[CH2:8]([O:15][C:16]([C@@H:18]1[CH2:22][C@@H:21]([F:23])[CH2:20][N:19]1[C:25](=[O:26])[NH:24][C:27]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[N:29]([C:36](=[O:37])[NH2:38])[CH:28]=1)=[O:17])[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1