Trifluoroacetic acid → (3-Aminomethyl-5-chloro-4-fluoro-phenyl)-diethyl-amine
反応式
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[C:13]([N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])[CH:12]=[C:11]([Cl:20])[C:10]=1[F:21])(C)(C)C.C(O)(C(F)(F)F)=O>C(Cl)Cl>[NH2:7][CH2:8][C:9]1[CH:14]=[C:13]([N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])[CH:12]=[C:11]([Cl:20])[C:10]=1[F:21]参加物
4
実験手順
was prepared according to Scheme C1 (step B) from (3-chloro-5-diethylamino-2-fluoro-benzyl)-carbamic acid tert-butyl ester and TFA in CH2Cl2. MS (LC-MS): 231.0 [M]+; tR (HPLC conditions c): 2.29 min.
後処理
- customwas prepared
- custom2.29 min.
出典と根拠
- ORDレコード
- ord-4aec3db98f8a4bc98b3ea59a082503b2
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09085555B2
反応ノート
読み込み中…