HCID 86686556、化合物 → HCID 86686557、化合物
反応式
[F:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH3:16])([CH3:15])[C:5](=[O:14])[NH:6]2>[Pd].CO>[NH2:11][C:10]1[C:2]([F:1])=[C:3]2[C:7](=[CH:8][CH:9]=1)[NH:6][C:5](=[O:14])[C:4]2([CH3:15])[CH3:16]参加物
4
実験手順
A suspension of 4-fluoro-3,3-dimethyl-5-nitro-1,3-dihydro-2H-indol-2-one (3.5 g), palladium on carbon (containing water (50%), 2.0 g) in methanol (150 mL) was stirred at room temperature for 3 hr under a hydrogen atmosphere. The palladium on carbon was removed by filtration, and the filtrate was concentrated under reduced pressure to give the title compound (2.9 g).
後処理
- customThe palladium on carbon was removed by filtration
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-d1901db62d9f45908933aa299b6b072e
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09090586B2
反応ノート
読み込み中…