HCID 89525566、化合物 → C-(5-methylfuran-2-yl)-C-(3-methyloxetan-3-yl)methylamine
反応式
[N:1]([CH:4]([C:11]1([CH3:15])[CH2:14][O:13][CH2:12]1)[C:5]1[O:6][C:7]([CH3:10])=[CH:8][CH:9]=1)=[N+]=[N-].[H][H]>C(O)C.[Pd]>[CH3:10][C:7]1[O:6][C:5]([CH:4]([NH2:1])[C:11]2([CH3:15])[CH2:12][O:13][CH2:14]2)=[CH:9][CH:8]=1参加物
5
実験手順
A solution of 1.68 g (8 mmol, 1 eq) of 2-[azido-(3-methyloxetan-3-yl)methyl]-5-methylfuran in 30 ml of ethanol in the presence of 252 mg (15% by weight) of palladium on carbon at 10% was stirred at hydrogen atmospheric pressure for 3 hours. The reaction medium was filtered and the filtrate was evaporated. 1.42 g of C-(5-methylfuran-2-yl)-C-(3-methyloxetan-3-yl)methylamine were obtained in the form of a greenish oil. Yield=98%.
後処理
- filtrationThe reaction medium was filtered
- customthe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-0f95d1c70e0145198158ee2e451d261a
- 出典データセット
- uspto-grants-2015_07
- 特許番号
- US09090596B2
反応ノート
読み込み中…