HCID 21989850、化合物 → 7-Amino-2(3H)-benzoxazolone

HRID 1528189ノート

反応式

HRID 1528189 の反応式
[N+:1]([C:4]1[C:12]2[O:11][C:10](=[O:13])[NH:9][C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[C:12]2[O:11][C:10](=[O:13])[NH:9][C:8]=2[CH:7]=[CH:6][CH:5]=1

参加物

4

反応物 1

HCID 21989850HCID 21989850、化合物

生成物 1

HCID 111478147-Amino-2(3H)-benzoxazolone収率 99.7%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 0.3 g of 7-nitro-3H-benzooxazol-2-one (1.67 mmol) in 5 ml of ethanol was degassed and then 0.03 g (10% by weight) of palladium on carbon (5%-50% wet) was added thereto. The reaction medium was stirred under a hydrogen atmosphere for 2 hours at ambient temperature. The reaction medium was filtered through celite and concentrated to dryness. 0.25 g of product was obtained in the form of a colorless oil. Yield=99%.

後処理

  1. filtrationThe reaction medium was filtered through celite and
  2. concentrationconcentrated to dryness

出典と根拠

ORDレコード
ord-9e33099efe9e4bc2be4729c9350c9ed9
出典データセット
uspto-grants-2015_07
特許番号
US09090596B2

反応ノート

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