Isatin → HCID 178517103、化合物
反応式
[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=O)[C:2]1=[O:3].Cl.[NH2:13][OH:14].C([O-])(=O)C.[Na+]>C(O)C.O>[OH:14][N:13]=[C:4]1[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[NH:1][C:2]1=[O:3]参加物
6
実験手順
To a suspension of 73.6 g of isatin in 1.2 l of ethanol was added a solution of 64.1 g of hydroxylamine hydrochloride and 64.1 g of sodium acetate in 500 ml of water. The mixture was stirred at room temperature for 30 minutes and concentrated. The residue was washed with water and recrystallized from ethanol to give 51.8 g (64%) of 3-(hydroxyimino)indolin-2-one as yellow crystals.
後処理
- concentrationconcentrated
- washThe residue was washed with water
- customrecrystallized from ethanol
出典と根拠
- ORDレコード
- ord-abd1439ced1d4ae5952032b23374c2f9
- 出典データセット
- uspto-grants-2001_03
- 特許番号
- US06207836B1
反応ノート
読み込み中…